Lately, I have become increasingly interested in quantitative physiology, focusing on how global cellular properties, such as growth rate and resource allocation, emerge from the interplay of molecular processes. This approach seeks to connect gene expression regulation with broader principles governing cell growth and adaptation.
I specialize in understanding the determinants of mRNA translation, including initiation dynamics, codon usage, transcript length (and their broader impact on cellular physiology). By examining how these factors influence translation efficiency and protein synthesis, my research aims to bridge the gap between molecular mechanisms and cellular-scale behaviors.
My work often employs models like the Totally Asymmetric Simple Exclusion Process (TASEP), which provide a powerful framework to study biosynthesis fluxes (RNAP and ribosome traffic). However, I’m also interested in studying this non-equilibrium model from a more theoretical point of view.